HOST CELLS AND METHODS USEFUL FOR PRODUCING UNNATURAL TERPENOIDS USING A NOVEL ARTIFICIAL METALLOENZYME

摘要

The present invention provides for a genetically modified host cell capable of producing an unnatural compound, such as terpenoid, comprising a P450 enzyme comprising an artificial cofactor, and the host cell is capable of uptaking the artificial cofactor by comprising a heterologous heme transport transmembrane protein, or homologue thereof.