isolated nucleic acid, method for preparing a functional sesquiterpene synthase variant, synthase, polypeptide, vector, host cell, non-human organism, and methods for producing a recombinant host cell, a sesquiterpene synthase, and at least one terpenoid

摘要

"NUCLEIC ACID ISOLATED, METHOD FOR PREPARING A SQUITERPENE FUNCTIONAL SYNTASE VARIANT, SYNTASE, POLYPEPTID, VECTOR, HUMAN CELL, AND METHODS TO PRODUCE A HONEY CENEP, A SYNCHESIS The invention concerns sesquiterpene synthases of Patchuli (Pogostemon cablin) plants, and methods of their production and use. In one embodiment, the invention provides nucleic acids comprising a nucleotide sequence as described herein that encodes at least one sesquiterpene synthase. In another embodiment, the invention also takes into account sesquiterpene synthases and methods of producing and using these enzymes. For example, the sesquiterpene synthases of the invention may be used to transform farnesyl pyrophosphate into various sesquiterpenes, including patchulol, sym -curcumene and other germacrene-type sesquiteipenes.