CONDITIONED CULTURE SOLUTION, CANDIDATE COMPOUND FOR BILE EXCRETION SENSITIVITY BY HEPATOCYTES, AND EVALUATION METHOD FOR HEPATIC METABOLITE OF CANDIDATE COMPOUND

摘要

A candidate compound for a bile excretion sensitivity that is accumulated in a bile canaliculus-like structure among a plurality of hepatocytes, said hepatocytes having been cultured and activated on a collagen vitrigel membrane, and a conditioned culture solution that promotes the excretion of the hepatic metabolite of the candidate compound.