Topical Hazard Evaluation Program of Candidate Insect Repellent AI3-20816-a, US Department of Agriculture Proprietary Compound, September 1978-November 1980

摘要

A hazard evaluation of candidate insect repellent AI3-20816-a was performed by means of laboratory studies using rats, rabbits, and guinea pigs. The technical grade compound causes mild skin irritation, but no eye irritation, no photochemical irritation in rabbits, no sensitization reaction in guinea pigs, and did not demonstrate an acute ingestion hazard. However, 25 percent ethanol solutions of AI3-20816 cause moderate skin irritation reactions in rabbits. It is recommended that AI3-20816, USDA Proprietary compound be approved for further testing as a candidate insect repellent. Ethanol solutions may cause some skin irritation in sensitive individuals. (Author)