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TARGETING M2-LIKE TUMOR-ASSOCIATED MACROPHAGES BY USING MELITTIN-BASED PROAPOPTOTIC PEPTIDE
TARGETING M2-LIKE TUMOR-ASSOCIATED MACROPHAGES BY USING MELITTIN-BASED PROAPOPTOTIC PEPTIDE
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机译:使用基于Melittin的促进肽靶向M2样肿瘤相关的巨噬细胞
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摘要
The present invention relates to a melittin-anticancer drug conjugate in which melittin and an anticancer drug are conjugated, and to a method of preparing a melittin-anticancer drug conjugate by connecting melittin and an anticancer drug. A conjugate of the present invention is an anticancer material for targeting M2-type tumor-associated macrophages (TAM) and exhibits an excellent effect of selectively selecting M2-type tumor-associated macrophages (TAM), and thus may be used for a use of drug delivery for targeting M2-type tumor-associated macrophages.
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