APTAMER FOR ADAMTS5 AND USE FOR APTAMER FOR ADAMTS5

摘要

The present invention provides an aptamer containing a sequence shown by the following formula (1) or formula (2):; (1) GGGGCCUCC-N1-GGACYAAACC (2) GGGGCCUCC-N1-GGACWYAAACC wherein N1 shows 3 to 24 bases in length, Y is C or U, and W is A or U (uracil is optionally thymine), wherein the aptamer binds to a disintegrin and metalloproteinase with thrombospondin motifs-5 (ADAMTS5).