3-((1R, 3R) -1- (2,6-difluoro-4-((1- (3-fluoropropyl) azetidine-3-yl) amino) phenyl) -3-methyl-1,3,4 , 9-Tetrahydro-2H-pyrido 3,4-b indol-2-yl) -2,2-difluoropropan-1-ol condensed tricyclic compound containing solid form and substituted phenyl or pyridinyl moiety Methods for preparing and how to use them

摘要

Provided here are 3-((lR, 3R) -l- (2,6-difluoro-4-((l- (3-fluoropropyl) azetidine-3-yl) amino) phenyl) -3. -Methyl-l, 3,4,9-tetrahydro-2H-pyrido [3,4-b] indole-2-yl) -2,2-difluoropropane-l-ol solid form, salt, eg compound B, And formulations, their processes and synthesis, and their use in the treatment of cancer. [Selection diagram] None