Design device, design method, aptamer production method, and program

摘要

Problem to be solved: to provide a design apparatus capable of simplifying an aptamer array.In the design apparatus 1 of the present inventionCandidate aptamer sequence acquisition meansGet the candidate aptamer arrayThe candidate aptamer array isIdentified motif array containingEstimation meansThe candidate aptamer structure is estimated from the candidate aptamer sequence.The design meansRemove the base outside the motif arrayDesign a plurality of miniaturized aptamer arrays with different lengths from one candidate aptamer arrayEstimation meansAndThe structure of the miniaturized aptamer is estimated from the miniaturized aptamer sequence.Calculating meansCalculates the score for each miniaturized aptamer arrayThe scoreThe structure of the motif in the miniaturized aptamer indicates the degree of formation of the motif structure in the candidate aptamerThe extraction meansA miniaturized aptamer array whose score is above a predetermined value is extracted.Diagram