Amide-substituted heterocyclic compounds for the treatment of conditions associated with modulation of IL-12, IL-23 and/or IFN-alpha

摘要

A compound having Formula I, or a stereoisomer or pharmaceutically acceptable salt thereof, wherein R 1 , R 2 , R 3 , R 4 , and R 5 are as defined herein, acts on Tyk-2 It is useful for modulation of IL-12, IL-23 and/or IFNα by causing signal transduction inhibition.