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Benzoxazoles and related compounds useful as modulators of chaperone-mediated autophagy

机译:苯并恶唑和相关的化合物可用作伴侣介导的自噬的调节剂

摘要

Disclosed are compounds of formula (I) and pharmaceutically acceptable salts thereof: [Formula I] Variables such as R 1 -R 9 , X and Y are defined herein. Certain compounds and salts of formula (I) are active as CMA modulators. The present disclosure provides pharmaceutical compositions containing compounds of formula (I) and methods of treating disorders responsive to CMA modulation.
机译:公开了式(I)化合物和其药学上可接受的盐:[式I]如R 1 -R 9-sup>,x和y定义。式(I)的某些化合物和盐作为CMA调节剂是活性的。本公开提供了含有式(I)化合物的药物组合物和响应于CMA调制治疗病症的方法。

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