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METHOD OF TREATMENT AND DEVICE FOR THE IMPROVED BIO AVAILABILITY OF MONTELUKAST, A LEUKOTRIENE RECEPTOR ANTAGONIST
METHOD OF TREATMENT AND DEVICE FOR THE IMPROVED BIO AVAILABILITY OF MONTELUKAST, A LEUKOTRIENE RECEPTOR ANTAGONIST
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机译:一种治疗方法和装置,用于改善蒙特利亚斯特的生物可用性,白肾上腺素受体拮抗剂
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摘要
Disclosed is a method of administration and device for the improved bioavailability of leukotriene receptor antagonists. This method and device involve an alkaline surface pH oral film dosage form designed to deliver leukotriene receptor antagonists, such as Montelukast, to the stomach in an amorphous precipitate suspended in aqueous medium. Also disclosed is a device and method for treating a disease, such as a neurodegenerative disease or condition associated with neuroinflanimation induced by a leukotriene. The device is a film unit dosage form having an alkaline surface pH film layer and a safe and effective amount of Montelukast. The device is configured and formulated to predominantly achieve enteral delivery of the Montelukast. The method includes enterally delivering to a human or an animal in need of treatment, a safe and effective amount of Montelukast capable of crossing the blood-brain barrier.
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