首页> 外国专利> ANTIBODY FOR HER2 CONCOMITANT DIAGNOSIS IMMUNOHISTOCHEMICAL DETECTION AND APPLICATION THEREOF

ANTIBODY FOR HER2 CONCOMITANT DIAGNOSIS IMMUNOHISTOCHEMICAL DETECTION AND APPLICATION THEREOF

机译:HER2的抗体伴随诊断免疫组化检测及其应用

摘要

The invention provides an antibody for human epidermal growth factor receptor 2 (Her2) concomitant diagnostic immunohistochemical detection (IHC). When the antibody is used as a primary antibody for immunohistochemical detection of Her2 expression, false positives in detection results caused by the absence of an extracellular region can be avoided. Moreover, the antibody can still recognize and bind to the corresponding epitope in the detection sample when the patient's immunohistochemical detection sample is not repaired by an antigen (or epitope), thereby reducing the issue of a false negative caused by the difference in repairing methods of the antigen (or epitope) in an IHC test.
机译:本发明提供了人表皮生长因子受体2(HER2)伴随诊断免疫组化检测(IHC)的抗体。当抗体用作用于HER2表达的免疫组织化学检测的一抗,可以避免由于不存在细胞外区域引起的检测结果中的误报。此外,当患者的免疫组织化学检测样品未被抗原(或表位)修复时,抗体仍然可以识别并结合检测样品中的相应表位,从而减少由修复方法的差异引起的假阴性问题IHC测试中的抗原(或表位)。

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