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Effect of Antibody Density on Immunotargeting and Radiographic Detection of HER2+ Breast Cancer Cells with Au@SiCh NPs

机译:抗体密度对Au @ SiCh NPs HER2 +乳腺癌细胞免疫定位和放射学检测的影响

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Immunotargeting HER2+ breast cancer cells with Au@SiO_2-anti-HER2 NPs was dependent on the number of antibodies/NP. Au@SiO_2-anti-HER2 NPs with -100 antibodies/NP exhibited highly specific targeting of HER2+ breast cancer cells in vitro, but with NPs with ~10 antibodies/NP did not.
机译:具有Au @ SiO_2-抗-HER2 NPs的免疫靶向HER2 +乳腺癌细胞取决于抗体/ NP的数量。具有-100个抗体/ NP的Au @ SiO_2-抗-HER2 NPs在体外对HER2 +乳腺癌细胞表现出高度特异性的靶向,但是具有〜10个抗体/ NP的NPs没有。

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