MICROBIAL PRODUCTION OF MOGROL AND MOGROSIDES

摘要

The present invention provides host cells and methods for making mogrol glycosides, including Mogroside V (Mog.V), Mogroside VI (Mog.VI), Iso-Mogroside V (Isomog. V), siamenoside, and glycosyiation products that are minor products in Siraitiagrosvenorii. The invention provides engineered enzymes and engineered host cells for producing mogrol glycosyiation products, such as Mog.V, Mog.VI, and Isomog. V, at high purity and/or yield. The present technology further provides methods of making products containing mogrol glycosides, such as Mog.V, Mog.VI, and Isomog. V, including food products, beverages, oral care products, sweeteners, and flavoring products.