A METHOD FOR METABOLITE SIGNAL QUANTITATION FOR MAGNETIC RESONANCE SPECTROSCOPY DATA

摘要

It is an integrative platform for visualization, preprocessing and quantitation of MRS data acquired using single voxel, multi voxel magnetic resonance spectroscopy imaging (MRSI) and MEshcher-GArwood Point-RESolved Spectroscopy (MEGA-PRESS) acquisition methods. The method integrates both time- and frequency-domain signal processing methods on a single platform. The method is optimized for proton (¹H) and phosphorous (³¹P) MRS data. It employs the use of iterative baseline estimation and fitting procedure to provide improved quantitation accuracy. The method can be used in both interactive and automatic mode to cater to the needs of researchers and clinicians.