首页> 外国专利> 1,3,4,9-TETRAHYDRO-2H-PYRIDO3,4-BINDOLE DERIVATIVE COMPOUNDS AND USES THEREOF

1,3,4,9-TETRAHYDRO-2H-PYRIDO3,4-BINDOLE DERIVATIVE COMPOUNDS AND USES THEREOF

机译：1,3,4,9-四氢-2H-吡啶[3,4-B]吲哚衍生物化合物及其用途

页面导航

摘要
著录项
相似文献

摘要

The present invention relates to 1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indole derivative compounds and uses thereof. In particular, compounds of the invention have antibacterial activity and/or are capable of re-sensitizing methicillin-resistant Staphylococcus aureus to a P-lactam antibiotic or a combination of a P-lactam antibiotic and a P-lactamase inhibitor. The present invention also relates to a method for producing and using said compounds.

机译：本发明涉及1,3,4,9-四氢-2H-吡啶[3,4-B]吲哚衍生物化合物及其用途。特别地，本发明化合物具有抗菌活性和/或能够将耐甲氧脲葡萄球菌的金黄色葡萄球菌重新敏化至p-lactam抗生素或p-lactam抗生素和p-酰胺酶抑制剂的组合。本发明还涉及制备和使用所述化合物的方法。

著录项

公开/公告号EP3836919A1

专利类型
公开/公告日2021-06-23

原文格式PDF
申请/专利权人 RECREO PHARMACEUTICALS INC.;
展开▼

申请/专利号EP20190849557
发明设计人 ZHANG JING;WANG XIANG;PODOLL JESSICA D.;
展开▼

申请日2019-08-15
分类号A61K31/404;A61K31/407;A61P31;C07D487/02;C07D487/04;
国家 EP
入库时间 2024-06-14 21:42:15

相似文献

专利
外文文献
中文文献

1. Design, Microwave Assisted Synthesis of Some Schiff Bases Derivatives of Congo Red and Conventional Preparation of Their Structurally Reversed Analogous Compounds [J] . Nashwan O. Tapabashi, Nihad I. Taha, Marwa El-Subeyhi 有机化学国际期刊（英文） . 2021,第001期

2. Synthesis Characterization and Biological Activities of an Enamine Derivative and Its Coordination Compounds [J] . Temitayo Aiyelabola, Johannes Jordaan, Daniel Otto, 生物化学进展（英文） . 2020,第006期

3. DFT and 3D-QSAR Studies of Anti-Cancer Agents m-(4-Morpholinoquinazolin-2-yl) Benzamide Derivatives for Novel Compounds Design [J] . ZHAO Siqi, ZHANG Guanglong, XIA Shuwei, 中国海洋大学学报（英文版） . 2018,第003期

4. Design and synthesis of the novel antibacterial agent 8-bromo-1,1-dimethyl-1,3,4,9-tetrahydropyrano3,4-bindole and its derivatives [C] . Yiqian Wang, Qi Yuan, Kui Lu, International Symposium on Information Technologies in Medicine and Education;ITME 2012 . 2012

5. Single-crystal X-ray investigations of the selected molecular crystals: Dicarbazoles, nitro derivatives of carbazolyl compounds and carbazolyl compound-tetracyanoethylene electron donor-acceptor complexes [D] . Chen, Zhenhua. 1993

6. A comparison of cinobufotenine (the quaternary derivative of 5-HT) and some related compounds with coryneine (the quaternary derivative of dopamine) on the frog rectus guinea-pig ileum and rat fundus strip preparations. [O] . R. B. Barlow, K. N. Burston 1980

7. Biological evaluation and structure activity relationship of 9-methyl-1-phenyl-9H-pyrido3,4-bindole derivatives as anti-leishmanial agents [O] . Penta Ashok, Subhash Chander, Terry K. Smith, 2019

1. A New Manganese(Ⅱ) Coordination Compound Constructed by 1,10-Phenanthroline Derivative and Chlorine Anions: Synthesis, Crystal Structure and Theoretical Calculation [J] . WANG Xiu-Yan ,GAO Wen-Yu ,ZHOU Xiao-Hang . 结构化学 . 2019,第005期

2. Synthesis, Fluorescence and Dielectric Properties of Two Novel Compounds Based on Triethylenediamine Derivatives [J] . DENG Si-Yu ,QIAN Xiu ,LI Mu . 结构化学 . 2019,第004期

3. 新型含四氢咪唑并吡啶酮结构的新烟碱类化合物的合成及生物活性研究 [C] . 王高磊 ,刘坤 ,陈希 . 第十三届全国农药交流会 . 2013

4. 1,3,4,9-四氢吡喃[3,4-b]吲哚类衍生物氧化去外消旋化研究 [A] . 路然 . 2018