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A pharmaceutical composition comprising at least one protein kinase inhibitor and a stable amorphous hybrid nanoparticles of at least one polymeric stabilized matrix forming ingredient

机译:一种药物组合物,其包含至少一种蛋白激酶抑制剂和至少一种聚合物稳定基质形成成分的稳定无定形杂交纳米颗粒

摘要

Problem to be solved: to provide a new pharmaceutical composition capable of improving the bioavailability and stability of the pharmacological active component in the pharmaceutical composition containing the water-soluble drug.Solution comprises at least one protein kinase inhibitor (nylonitib, etc.) and a stable amorphous solid dispersion particle of at least one polymeric stabilized matrix forming ingredient, optionally A pharmaceutical composition comprising at least one pharmacologically acceptable solubilizer.No selection
机译:要解决的问题:提供一种新的药物组合物,其能够改善含有水溶性药物的药物组合物中药理学活性组分的生物利用度和稳定性。溶液包含至少一种蛋白激酶抑制剂(尼龙等)和至少一种聚合物稳定基质形成成分的稳定的无定形固体分散颗粒,任选地是包含至少一种药理学上可接受的增溶剂的药物组合物。没有选择

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