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SYSTEMS AND METHODS FOR PRODUCING INJECTABLE ENHANCED STEM CELL EXOSOMES, IMPROVED EXOSOMES AND METHODS OF USE

机译:制备可注射增强干细胞外来的系统和方法,改善外泌体和使用方法

摘要

This disclosure pertains to a non-living biological product. Particularly, exosomes derived from stem cells can help restore heart function. According to certain embodiments, a fluid-induced shear stress mechanical stimulation process of stem cells is used to augmented quantity and quality of exosomes produced from stem cells. These exosomes serve as a therapeutic agent for the regenerative repair of diseases, such as diseased heart tissues. Therefore, compositions comprising the exosomes derived from stem cells and methods of treating a degenerative disease by administering the exosomes isolated from stem cells are also provided.
机译:本公开涉及非生物生物产品。特别地,衍生自干细胞的外泌体可以有助于恢复心脏功能。根据某些实施方案,干细胞的流体诱导的剪切应力机械刺激过程用于增强由干细胞产生的外索体的量和质量。这些外来物用作疾病的再生修复的治疗剂,例如患病的心脏组织。因此,还提供了包含衍生自干细胞的外泌体的组合物和通过施用从干细胞分离的外泌体治疗退行性疾病的方法。

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