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Hybrid peptide, set of hybrid peptides, composition, uses of the hybrid peptide, method for inducing an immune response and kits

机译:杂化肽,杂化肽,组合物,杂化肽的用途,诱导免疫应答和试剂盒的方法

摘要

The present invention relates to novel hybrid peptides developed from the combination of membrane surface protein peptide fragments present in anaplasmosis microorganisms, and in particular, bacteria of the species Anaplasma marginale. The present invention further relates to hybrid peptide sets, compositions and kits comprising such novel hybrid peptides, their uses and methods of inducing immune response. Each hybrid peptide, according to the present invention, comprises two or more peptide fragments of amino acid sequences as defined in the present invention linked together by means of a spacer element. The combined peptide fragments are protein peptide fragments of MSP1, MSP1a, MSP1b, MSP2, MSP2-HRV, MSP3, OMP7, OMP8, VirB9 and VirB10.
机译:本发明涉及从腹膜症微生物中存在的膜表面蛋白肽片段的组合产生的新型杂化肽,特别是物种的细菌 anaplasma marginale 。本发明还涉及包含这种新型杂交肽的组合物和试剂盒,其用途和诱导免疫应答的方法。根据本发明的每种杂化肽包括通过间隔元件连接在一起的本发明中限定的两种或更多种肽片段。组合的肽片段是MSP1,MSP1A,MSP1B,MSP2,MSP2-HRV,MSP3,OMP7,OMP8,VIRB9和VIVB10的蛋白肽片段。

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