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HYBRID PEPTIDE, SET OF HYBRID PEPTIDES, COMPOSITION, USES OF THE HYBRID PEPTIDE, METHOD FOR INDUCING AN IMMUNE RESPONSE AND KITS

机译:混合肽,混合肽组,组成,混合肽的用途,诱发免疫反应的方法和试剂盒

摘要

The present invention relates to novel hybrid peptides developed from the combination of membrane surface protein peptide fragments present in anaplasmosis microorganisms, and in particular, bacteria of the species Anaplasma marginale. The present invention further relates to hybrid peptide sets, compositions and kits comprising such novel hybrid peptides, their uses and methods of inducing immune response. Each hybrid peptide, according to the present invention, comprises two or more peptide fragments of amino acid sequences as defined in the present invention linked together by means of a spacer element. The combined peptide fragments are protein peptide fragments of MSP1, MSP1a, MSP1b, MSP2, MSP2-HRV, MSP3, OMP7, OMP8, VirB9 and VirB10.
机译:本发明涉及新颖的杂合肽,该杂合肽是由存在于厌氧微生物中的膜表面蛋白肽片段的组合开发的,特别是边缘无浆膜物种的细菌。本发明还涉及杂合肽组。 ,包含此类新型杂合肽的组合物和试剂盒,其用途和诱导免疫应答的方法。根据本发明,每个杂合肽包含两个或多个通过间隔元件连接在一起的如本发明所定义的氨基酸序列的肽片段。组合的肽片段是MSP1,MSP1a,MSP1b,MSP2,MSP2-HRV,MSP3,OMP7,OMP8,VirB9和VirB10的蛋白肽片段。

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