PROCESS FOR OBTAINING POLYMER NANOPARTICLES FOR RECEPTOR-MEDIATED DRUG DELIVERY

摘要

The present invention relates to a process for obtaining polymer nanoparticles stabilised with a non-ionic polymer surfactant functionalised with a ligand, for receptor-mediated drug delivery. The distinctive feature of the invention is that said functionalisation is physical, through association in the stabiliser and the ligand, as opposed to other patents in which functionalisation is chemical. The invention also relates to the use of a methodology based on interfacial tension measurements and reported in scientific literature, to evaluate the capacity of the stabiliser to associate with ligand molecules.