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KIT FOR MEASURING ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY, APPLICATION THEREOF, AND TEST METHOD

机译:用于测量抗循环瓜氨酸肽抗体,其应用及试验方法的试剂盒

摘要

A kit for measuring an anti-cyclic citrullinated peptide antibody, an application thereof, and a test method is provided. The kit includes a biotinylated antigen formed by coupling a plurality of branched peptide units having branched peptide chains using lysine, and the branched peptide units each is formed by coupling a plurality of citrullinated peptides using lysine. The kit and method have high test sensitivity and good specificity; compared with a mixed antigen, citrulline being coupled and then used as a single-component antigen, reduces the complexity of components of the antigen and the difficulty of quality control of the reagent, and improves inter-batch consistency, and quantitative test can be performed and the time needed to complete all procedures to obtain a result is 45 min.
机译:提供用于测量抗循环瓜粉肽抗体,其应用及试验方法的试剂盒。该试剂盒包括通过使用赖氨酸偶联具有支链肽链的多个支链肽单元而形成的生物素化抗原,并且支化肽单元各自通过使用赖氨酸偶联多个瓜氨酸肽形成。试剂盒和方法具有高测试敏感性和良好特异性;与混合抗原相比,瓜氨酸偶联,然后用作单组分抗原,降低了抗原的组分的复杂性和试剂的质量控制的难度,并提高了间歇一致性,并且可以进行定量测试完成所有程序所需的时间是45分钟。

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