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Preparative scale conversion of gonyautoxins to neosaxitoxin
Preparative scale conversion of gonyautoxins to neosaxitoxin
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机译:甘达毒素的准备规模转化为新含沙素蛋白
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摘要
A method of preparing neosaxitoxin in quantities of a purity sufficient to allow the compound to be used as an active pharmaceutical ingredient (API) is described. The method includes the reductive desulfonation of an unresolved mixture of gonyautoxin 1 (GTX1) and gonyautoxin 4 (GTX4).
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