Contrast agent for optical imaging for early diagnosing rheumatoid arthritis

摘要

The present invention relates to an optical imaging contrast agent composition for early diagnosis of rheumatoid arthritis and a method of manufacturing the same, and more particularly, to a gold nanoparticle; And a polyethyleneglycol (PEG) coating layer formed to surround the surface of the gold nanoparticles, and further comprising a plurality of proteins G (protein G) located on the gold nanoparticles and an antibody linked to the protein G, or , It relates to a contrast medium composition for diagnosing arthritis further comprising a peptide represented by SEQ ID NO: 1 connected to the polyethylene glycol coating layer.