Dosage forms with prolonged release of tapentadol phosphoric acid salt

摘要

a Tapentadol complete pharmaceutical dosage form for twice daily oral administration;where tapethadol is present as a salt with phosphoric acid;where the dosage form provides an extended release of tapenade dol;where the equivalent weight of Tapentadol in the pharmaceutical formulation is 10 to 300 mg in terms of the free base of Tapentadol;where the dosage form is multiparticulate; andwhere the individual particles comprise a coating with an extended release comprising a coating material with an extended release.