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PLATINUM SULFIDE PROTEIN NANOPARTICLE HAVING NEAR-INFRARED PHOTOTHERMAL EFFECT AND MULTI-MODAL IMAGING FUNCTION, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
PLATINUM SULFIDE PROTEIN NANOPARTICLE HAVING NEAR-INFRARED PHOTOTHERMAL EFFECT AND MULTI-MODAL IMAGING FUNCTION, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
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机译:铂硫化物蛋白纳米粒子具有近红外光热效应和多模态成像功能,制备方法及其应用
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摘要
A platinum sulfide protein nanoparticle having near-infrared photothermal effect and multi-modal imaging function, a preparation method therefor and an application thereof. The platinum sulfide nanoparticle having near-infrared photothermal effect and multi-modal imaging function is prepared in aqueous phase by means of formulation screening and process limitation. The nanoparticle has an ultra-small particle size and good stability as well as tumor targeting and photothermal effects and integrates functions of near-infrared imaging, CT imaging, and thermal imaging, so as to achieve high sensitivity, high resolution, and precise positioning of tumors, and to produce high-efficiency photothermal effects under the excitation of near-infrared light to kill tumor cells by thermal ablation, thereby achieving the purpose of efficient, safe, visual, and accurate treatment of tumors. The nanoparticle has the potential for further development and clinical application.
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