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PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING GOSSYPOL, PHENFORMIN, AND ANTICANCER AGENT
PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING GOSSYPOL, PHENFORMIN, AND ANTICANCER AGENT
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机译:用于预防或治疗癌症的药物组合物,包含钆醇,苯甲酸和抗癌剂
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摘要
The present disclosure relates to a pharmaceutical composition comprising a combination of anticancer agents, capable of creating a synergistic effect when co-administer in the treatment of cancer, and more specifically, the present invention suggests anticancer agenst capable of creating a synergistic effect when co-administered with gossypol and phenformin. The anticancer agents selected as said anticancer agents in the present disclosure are sorafenib, vemurafenib, irinotecan, cisplatin, paclitaxel, and doxorubicin, and each of the aforementioned anticancer agent, when co-administered as a triple-drug combination with gossypol and phenformin can provide a significant synergistic effect in terms of the effect of suppressing the proliferation of cancer and killing cancer cell, compared to each mono-drug treatment group and a dual-drug treatment group of gossypol + phenformin.
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