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RNA INTERFERENCE-INDUCING NUCLEIC ACID INHIBITING NONCANONICAL TARGETS OF MICRO RNA, AND USE FOR SAME

机译:RNA干扰诱导核酸抑制微RNA的非甘露糖靶,并使用它

摘要

The present invention relates to RNA interference-inducing nucleic acid that inhibits noncanonical target genes of micro RNA, in which part of the sequence of a specific micro RNA has been modified, and by using the RNA interference-inducing nucleic acid of the present invention, the biological function micro RNA exhibits by inhibiting noncanonical target genes is effectively increased or there is the benefit of selectively exhibiting only one of the biological functions of conventional micro RNA, i.e., the function of inhibiting noncanonical target genes, and the interference-inducing nucleic acid of the present invention enables cell cycling, differentiation, dedifferentiation, formation, movement, splitting, proliferation or death adjustment, and it is expected that the invention can be used in various fields such as drugs and cosmetics.
机译:本发明涉及RNA干涉诱导的核酸,其抑制微RNA的非甘露糖靶基因,其中已经改变了特定微RNA的序列的一部分,并且通过使用本发明的RNA干涉诱导的核酸,通过抑制非甘露糖靶基因的生物功能微RNA表现出现有效或有益智选择性地表现出常规微RNA的生物学功能之一,即抑制非甘露出靶基因的功能,以及诱导干涉核酸的功能在本发明中,能够进行细胞循环,分化,消膜,形成,运动,分裂,增殖或死亡调节,并且预期本发明可以用于各种领域,例如药物和化妆品。

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