首页> 外国专利> ANTIBODY BINDING TO CHONDROITIN SULFATE PROTEOGLYCAN-5

ANTIBODY BINDING TO CHONDROITIN SULFATE PROTEOGLYCAN-5

机译:抗体与硫酸软骨素蛋白多糖-5的抗体结合

摘要

The invention relates to an antibody which binds to chondroitin sulfate proteoglycan 5 (CSPG5) or an antibody fragment thereof, a hybridoma which produces the antibody or the antibody fragment thereof, a nucleic acid comprising a nucleotide sequence encoding the antibody or the antibody fragment thereof, a transformant cell comprising a vector comprising the nucleic acid, a method for producing the antibody or the antibody fragment thereof, a composition comprising the antibody or the antibody fragment thereof, and a method for detecting or measuring an antigen present in the brain, a method for diagnosing or treating a brain disease, a method for enhancing the property of accumulating in a brain of an antibody, and a method for increasing the amount of an antibody in the brain, each of which using the antibody or the antibody fragment thereof, and the like.
机译:本发明涉及与硫酸软骨素蛋白多糖5(CSPG5)或其抗体片段结合的抗体,其产生抗体或其抗体片段的杂交瘤,该核酸包含编码抗体的核苷酸序列或其抗体片段,包含含有核酸的载体的转化细胞,一种用于产生抗体或其抗体片段的方法,包含抗体或其抗体片段的组合物,以及用于检测或测量脑中存在的抗原的方法,方法用于诊断或治疗脑疾病,一种用于增强累积在抗体的脑中的性质的方法,以及用于增加脑中抗体的量的方法,每个使用抗体或其抗体片段和抗体片段类似。

著录项

  • 公开/公告号EP3816291A1

    专利类型

  • 公开/公告日2021-05-05

    原文格式PDF

  • 申请/专利权人 KYOWA KIRIN CO. LTD.;KAGOSHIMA UNIVERSITY;

    申请/专利号EP20190826585

  • 申请日2019-06-26

  • 分类号C12N15/13;A61K39/395;A61K47/56;A61K47/60;A61K47/68;A61K50;A61K51/10;A61P25;A61P29;A61P35;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12P21/08;

  • 国家 EP

  • 入库时间 2022-08-24 18:32:51

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