Antibodies that bind to chondroitin sulfate proteoglycan-5

摘要

The present invention provides an antibody or a corresponding antibody fragment that binds to chondroitin sulfate proteoglycan 5 (CSPG5), a hybridoma producing the antibody or the antibody fragment, and a base sequence encoding the antibody or the antibody fragment. A nucleic acid containing, a transformed cell containing a vector containing the nucleic acid, a method for producing the antibody or antibody fragment, the antibody or composition containing the antibody fragment, and present in the brain using the antibody or the antibody fragment. It relates to a method of detecting or measuring an antigen, a method of diagnosing or treating a brain disease, a method of improving the brain retention of an antibody, a method of increasing the amount of antibody in the brain, and the like.