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Delivery of hydrophobic bioactive material particles

机译:疏水性生物活性材料颗粒

摘要

PROBLEM TO BE SOLVED: To provide a drug delivery coating. SOLUTION: The drug delivery coating and a device including the drug delivery coating are included. In one embodiment, it comprises a drug delivery coating that includes a polymer layer. The polymer layer can include a hydrophilic outer surface. The coating can also include a matrix that is in contact with the hydrophilic outer surface. The matrix can include particulate hydrophobic therapeutic agents and cationic agents. The polymer layer can further include a hydrophilic polymer having a photoreactive group of pendants and a photosensitive cross-linking agent containing two aryl ketone functional groups. [Selection diagram] None
机译:要解决的问题:提供药物递送涂层。溶液:包括药物递送涂层和包括药物递送涂层的装置。在一个实施方案中,它包括包含聚合物层的药物递送涂层。聚合物层可包括亲水性外表面。涂层还可包括与亲水外表面接触的基质。基质可包括颗粒状疏水性治疗剂和阳离子剂。聚合物层还可包括具有含有两种芳基酮官能团的光敏反应性的坠子和光敏交联剂的亲水性聚合物。 [选择图]无

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