CALIBRATION OF RADIATION DOSE ESTIMATION IN MEDICAL NUCLEAR IMAGING

摘要

For calibration of internal dose in nuclear imaging, the dose model used for estimating (58) internal dose in a patient is calibrated (56). One or more values of the dose model (e.g., a physics simulation, dose kernels, or a transport model) are set based on measured dose. The dose may be measured (54) relative to specific tissues and/or isotopes, providing for tracer and tissue specific calibration (56). For example, dose from the tracer to be injected into the patient is estimated (52) from emissions as well as measured (54) by a dosimeter (42) in a tissue mimicking tissue mimicking object (40). These doses are used to calibrate (56) the dose model, which calibrated dose model is then used to determine (58) internal dose for the patient.