METHOD FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF BREAST CANCER METASTASIS

摘要

The present invention relates to a method for diagnosing or prognosing breast cancer metastasis, comprising determining whether the c-MAF gene is amplified in a primary tumor sample. Further, the present invention is a method for diagnosing or prognosing ER- breast cancer metastasis, comprising measuring the expression level of the c-MAF gene, and measuring a tendency to develop metastasis to bone in contrast to metastasis to other organs. It''s about the method. Finally, the present invention relates to the use of a c-MAF inhibitor as a therapeutic agent for treating ER- breast cancer metastasis.