A Biosensor for detection of Avian Influenza

摘要

The present invention relates to a composition comprising a multifunctional DNA construct capable of simultaneously performing various functions in one DNA construct by using DNA 3WJ, a DNA construct having a 3-way junction. In particular, at the ends of the three DNA strands, a detection unit that specifically binds to hemagglutinin (HA) of H5N1 type avian influenza (AI), and hemagglutinin of H5N1 type avian influenza (AI) ( A signal part that inhibits electron transfer to the outside when hemagglutinin, HA) is bound, and a fixing part that immobilizes the composition on the outer surface are combined. In addition, it relates to a biosensor and kit for detecting H5N1 type avian influenza based on electrochemistry comprising the composition. In addition, an improved electrochemical signal can be obtained by additionally using porous Au Nanospike in the biosensor.