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NEW APPLICATIONS OF RIFAMYCIN-NITROIMIDAZOLE COUPLING MOLECULES
NEW APPLICATIONS OF RIFAMYCIN-NITROIMIDAZOLE COUPLING MOLECULES
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机译:利福莫霉素 - 硝基咪唑偶联分子的新应用
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摘要
The present invention discloses a use of a rifamycin-nitroimidazole conjugate molecule shown in formula I against anaerobic bacteria. The rifamycin-nitroimidazole conjugate molecule shown in formula I of the present invention has broad-spectrum antibacterial activity against anaerobic bacteria, including activity against most pathogenic bacteria associated with bacterial vaginosis, in vitro antibacterial activity stronger than that of drugs against bacterial vaginosis such as metronidazole and clindamycin, and potential use in prevention and treatment of bacterial vaginosis or other related diseases caused by anaerobic bacteria.
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