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METHOD FOR IDENTIFYING GENE PRODUCTS INVOLVED IN INCOMPLETE RESPONSE OF DRUG SENSITIVE CELL POPULATIONS

机译:鉴定参与药物敏感细胞群体不完全反应的基因产物的方法

摘要

The present invention relates to an in vitro method for identifying a gene product involved in fractional killing of drug sensitive cell populations following cancer drug treatment and a combined preparation comprising a cancer drug and a compound that modulates the expression or the activity of the gene product identified by said method for use in cancer treatment to increase said cancer drug potency and reduce the development of resistance to said cancer treatment.
机译:本发明涉及癌症药物治疗后鉴定癌症敏感细胞群的分数杀死中涉及的基因产物的方法,以及包含癌症药物和调节表达的化合物的组合制剂通过所述癌症治疗方法鉴定的基因产物的活性增加所述癌症药物效力并降低抗癌症治疗的抗性的发展。

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