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SYNTHESIS METHOD APPLIED TO KRAS INHIBITOR DRUG HETEROCYCLIC INTERMEDIATE

机译:合成方法应用于KRAS抑制剂药物杂环中间体

摘要

The present application provides a compound of formula II and a method for preparing a compound of formula I, i.e., 2-isopropyl-4-methylpyridin-3-amine by using same. The compound of formula I can be applied to synthesis of KRAS inhibitor drugs. The raw materials involved in the method of the present application are easy to obtain and low in price, operation is easy and convenient, economization and environmental protection are achieved, and industrial production is facilitated.
机译:本申请提供了式II化合物和制备式I化合物,即2-异丙基-4-甲基吡啶-3-胺的制备方法。式I化合物可以应用于KRAS抑制剂药物的合成。涉及本申请方法的原料易于获得,价格低,操作简便方便,实现了节约和环保,促进了工业生产。

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