NUCLEOTIDE-BASED NANOSWITCH AND METHODS FOR THE DETECTION OF ANTIBODIES AND OTHER ANALYTES

摘要

A nucleotide-based nanoswitch system for detecting one or more targets in a sample which includes a set of two or more oligonucleotide probes configured to provide a target binding-induced structural change of one or more of the oligonucleotide probes triggered by an increase in local concentration of the two or more oligonucleotide probes.