首页> 外国专利> METHOD FOR PRODUCING XENOGRAFT MODEL DERIVED FROM A PATIENT OF BREAST CANCER

METHOD FOR PRODUCING XENOGRAFT MODEL DERIVED FROM A PATIENT OF BREAST CANCER

机译:产生患有乳腺癌患者的异种移植模型的方法

摘要

An object of the present invention is to provide a method for producing a breast cancer patient-derived tumor tissue xenograft animal model and a breast cancer patient-derived tumor tissue xenograft animal model in which breast cancer tissue derived from a breast cancer (Leu1780Pro mutant) patient is transplanted into an immunodeficient mouse. In addition, it is to provide a method of providing information for selecting a breast cancer treatment tailored to breast cancer patients using the animal model described above. Since the tumor tissue xenograft animal model derived from a breast cancer patient of the present invention can provide conditions that have the same genetic, physiological and environmental characteristics as that of a Korean-specific breast cancer patient, the target anticancer drug candidate screening and breast cancer treatment of breast cancer patients It is expected to be greatly utilized.
机译:本发明的一个目的是提供一种制备乳腺癌患者衍生的肿瘤组织异种移植动物模型的方法和乳腺癌患者衍生的肿瘤组织异种移植动物模型,其中来自乳腺癌的乳腺癌组织(Leu1780Pro突变体)患者移植到免疫缺陷鼠中。此外,它是提供一种提供用于使用上述动物模型对乳腺癌患者进行定制的乳腺癌治疗的信息的方法。由于来自本发明的乳腺癌患者的肿瘤组织异种移植动物模型可以提供具有与韩国特异性乳腺癌患者的遗传,生理和环境特征具有相同的遗传,生理和环境特征的条件,其目标抗癌药物候选筛选和乳腺癌治疗乳腺癌患者预计将大大利用。

著录项

  • 公开/公告号KR102226485B1

    专利类型

  • 公开/公告日2021-03-11

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR1020170066300

  • 发明设计人 박형석;손주혁;김승일;이정동;

    申请日2017-05-29

  • 分类号A01K67/027;G01N33/50;

  • 国家 KR

  • 入库时间 2022-08-24 17:40:49

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