首页> 外国专利> Alpha monoglucosyl leufolin, method for producing α monoglucosyl leufolin, lipase inhibitor containing α monoglucosyl leufolin, and anti-glycation agent

Alpha monoglucosyl leufolin, method for producing α monoglucosyl leufolin, lipase inhibitor containing α monoglucosyl leufolin, and anti-glycation agent

机译:α单葡萄糖基Leufolin,制备α单葡萄糖烯胺,含α单葡萄糖基Leufolin的脂肪酶抑制剂和抗糖糖苷

摘要

PROBLEM TO BE SOLVED: To provide novel flavonoid glycosides, production methods thereof, and physiological applied products of novel flavonoid glycosides.SOLUTION: The present invention provides an α mono-glucosyl rhoifolin, and the following production method, as well as an anti-saccharification agent, lipase inhibitor, and the like containing α mono-glucosyl rhoifolin as an active ingredient. Step (1): A first reaction step (sugar transfer) of allowing a first enzyme to act on the sugar chain of an α-1,4-glucan in conditions in which the α-1,4-glucan, rhoifolin, and an aqueous solvent are present, cutting out glucose from the sugar chain of the α-1,4-glucan, and transferring the glucose to at least position 3" of the first sugar of the rhoifolin; Step (2): A second reaction step (sugar chain arrangement) of allowing a second enzyme having α-1,4-glucosidase activity to act on an α glucosyl rhoifolin group, which is obtained by the first reaction step, having one or more α glucosyl groups, and increasing the concentration (purity) of α mono-glucosyl rhoifolin by removing all α-1,4-glucosyl groups of the α glucosyl rhoifolin.SELECTED DRAWING: None
机译:要解决的问题:提供新型类黄酮糖苷,其生产方法,以及新的类黄酮糖苷的生理应用产物。溶液:本发明提供了一种α单 - 葡萄糖基Rhoifolin,以及以下的制备方法,以及抗糖化含有α单 - 葡萄糖基Rhoifolin的剂,脂肪酶抑制剂等作为活性成分。步骤(1):第一反应步骤(糖转移)允许第一酶作用于α-1,4-葡聚糖的糖链,其中α-1,4-葡聚糖,rhoifolin和一个存在含水溶剂,从α-1,4-葡聚糖的糖链切割葡萄糖,并将葡萄糖转移到rhoifolin的第一糖的至少位置3“;步骤(2):第二反应步骤(糖链装置,允许具有α-1,4-葡萄糖苷酶活性的第二酶作用于通过第一反应步骤获得的α葡糖糖苷基团,其具有一个或多个α葡萄糖基,并增加浓度(纯度通过除去α葡萄糖型rhoifolin的所有α-1,4-葡萄糖基的α单糖基罗素蛋白。选择的绘图:无

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