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TROPIC CELL BASED VIROTHERAPY FOR THE TREATMENT OF CANCER
TROPIC CELL BASED VIROTHERAPY FOR THE TREATMENT OF CANCER
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机译:基于热带细胞的病毒治疗癌症
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摘要
In some embodiments, methods of killing tumor cells are provided. The methods may include contacting the tumor cell with a tropic cell that carries a modified oncolytic virus, wherein the virus comprises a tumor selective element and/or a capsid protein that binds a tumor-specific cell surface molecule. In another embodiment, methods of treating cancer are provided. The methods may include administering a therapeutically effective amount of a pharmaceutical composition to a subject, wherein the pharmaceutical composition includes a tropic cell that carries a modified oncolytic virus, wherein the virus comprises a tumor selective promoter element and/or a capsid protein that binds a tumor-specific cell surface molecule.
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