首页> 外国专利> METHOD AND A SYSTEM FOR QUANTITATIVE OR QUALITATIVE DETERMINATION OF A TARGET COMPONENT

METHOD AND A SYSTEM FOR QUANTITATIVE OR QUALITATIVE DETERMINATION OF A TARGET COMPONENT

机译:方法和用于定量或定性测定目标组分的系统

摘要

A method and a system for quantitative or qualitative determination of a target component in a liquid sample. The method includes i) providing a plurality of magnetic particles including capture sites for the target component on their respective surfaces; ii) providing a plurality of fluorophores configured to bind to the capture sites of the magnetic particles; iii) bringing the liquid sample into contact with the fluorophores and the magnetic particles in a flow channel of a micro fluidic device including a transparent window; and iv) at least temporally immobilizing the magnetic particles adjacent to the transparent window using a magnet, emitting exciting electromagnetic beam towards the immobilized magnetic particles, reading signals emitted from fluorophores and performing a quantitative or qualitative determination of the target component based on the read signal. A suitable micro fluidic device for use in the method/system and a kit for preparing a liquid sample.
机译:一种方法和系统,用于定量或定性测定液体样品中的靶分量。该方法包括i),提供多个磁性颗粒,包括在它们各自的表面上的靶部件的捕获部位; ii)提供多个荧光团,被配置为与磁性颗粒的捕获位点结合; III)使液体样品与荧光团和磁性颗粒接触,在包括透明窗口的微流体装置的流动通道中;和IV)至少在读取荧光团向固定的磁性颗粒上发射励磁电磁束邻近透明窗口附近的磁性颗粒,读取从荧光团发射的信号并基于读取信号进行定量或定性确定目标分量的定量或定性确定。用于方法/系统的合适的微流体装置和用于制备液体样品的试剂盒。

著录项

  • 公开/公告号US2021063388A1

    专利类型

  • 公开/公告日2021-03-04

    原文格式PDF

  • 申请/专利权人 ZOETIS DENMARK APS;

    申请/专利号US202017090244

  • 申请日2020-11-05

  • 分类号G01N33/543;B01L3;G01N33/58;G01N33/50;G01N33/53;G01N33/569;B82Y15;G01N21/64;G01N33/04;G01N33/12;

  • 国家 US

  • 入库时间 2022-08-24 17:30:09

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