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2 - hydroxy - 3 - (2 - hydroxy 4 (2,4 - di - hydroxybenzylidenimino) - phenyl 1, 3, 4 - oxadiazol and its manufacture method
2 - hydroxy - 3 - (2 - hydroxy 4 (2,4 - di - hydroxybenzylidenimino) - phenyl 1, 3, 4 - oxadiazol and its manufacture method
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机译:2-羟基-3-(2-羟基4(2,4-二羟基苄叉亚氨基)-苯基1,3,4-恶二唑及其制造方法
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摘要
The compound of the formula FORM:1099101/C2/1 is prepared by reacting N2-(2,4-dihydroxybenzylidene) - isoncotinyl hydrazide with 2-hydroxy - 5 - (21 - hydroxy - 41 - aminophenyl) - 1,3,4-oxadiazole, and a water-soluble derivative thereof is prepared by reacting the product with rongalite. Pharmaceutical compositions comprise the above compound or its derivative with rongalite, and a carrier. The compositions, which have antitubercular properties, are formulated as tablets, capsules or solutions for injection.
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