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analogifremgangsmaade for the manufacture of alkyl 2 - (2 - amino - aetyltio) - glykolater or syreadditionssalte thereof with organiskeeller inorganic acids
analogifremgangsmaade for the manufacture of alkyl 2 - (2 - amino - aetyltio) - glykolater or syreadditionssalte thereof with organiskeeller inorganic acids
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机译:用有机硅酮无机酸生产烷基2-(2-氨基-乙炔基)-甘草酸酯或其合成盐的类似物
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1284505 Condensation products of glyoxylic acid esters with aminothiols LABORATOIRES HOUDE 8 Dec 1970 [19 Dec 1969] 58175/70 Heading C2C Novel compounds of the Formulµ (A) and (B) wherein R is C 1-18 alkyl, RSP1/SP is hydrogen, carboxylic acid or ester with a C 1-18 alcohol, excluding compound (B) in which RSP1/SP is hydrogen and R is methyl or ethyl, and acid addition salts thereof may be prepared by reacting a compound (C): with an alkyl glyoxylate OCH.COOR or with a hemiacetal ester of the Formula (E): in the presence of an alcohol ROH. Compound (B) when RSP1/SP is hydrogen may be prepared by heating the corresponding compound (A) with an alcohol ROH. Pharmaceutical compositions of the compounds (A) or (B) with the usual excipients may be used for prevention and treatment of damage due to ionizing radiation and may be administered orally, parenterally, rectally or topically.
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