dexamethasone and betamethasone esters and their preparation

摘要

Cpds. (I):- (where R is -Me or ----Me; R' is H or Me; R" is COMe or COPh and n is 1-8) are prepd. by reacting beta- or dexa-methasone with R"NH.(CH2)n.CH(R').COCl. Thus (I; R = alpha-Me, R' = H, R" = COMe and n = 1) is prepd. from methasone and MeCONH.CH2CH2.CLCl