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9 - Isopropylidene - 9,10 - dihydroanthracene - 10 - carbonsaeure - ss - diethylamino - ethyl esters, their salts and a method for the production thereof.
9 - Isopropylidene - 9,10 - dihydroanthracene - 10 - carbonsaeure - ss - diethylamino - ethyl esters, their salts and a method for the production thereof.
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机译:9-异亚丙基-9,10-二氢蒽-10-碳七-ss-二乙氨基-乙基酯,它们的盐及其制备方法。
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摘要
Novel compounds of the general formula FORM:1078250/C2/1 (in which R1 and R2, which may be the same or different, represent alkyl groups contain 1-5 carbon atoms) are obtained by condensing 9 - isopropylidene - 9,10 - dihydroanthracene - 10-carboxylic acid chloride with a b -aminoethanol of the formula FORM:1078250/C2/2 wherein R1 and R2 are as defined above, e.g. b -dimethylamino-, b -diethylamino-, b -methylethylamino-, b -methylbutylamino-, b -methylisopropylamino or b -ethylbutylaminoethanol. The products form non-toxic acid addition salts. 9 - Isopropylidene - 9,10 - dihydroanthracene - 10 - carboxylic acid chloride is obtained from the corresponding acid with a dehydrating agent, e.g. thionyl chloride, phosphorus trichloride or phosphorus pentachloride. Pharmaceutical compositions containing the above novel compounds and having a spasmolytic activity are administered orally, parenterally, or rectally.
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