9 - Isopropylidene - 9,10 - dihydroanthracene - 10 - carbonsaeure - ss - diethylamino - ethyl esters, their salts and a method for the production thereof.

摘要

Novel compounds of the general formula FORM:1078250/C2/1 (in which R1 and R2, which may be the same or different, represent alkyl groups contain 1-5 carbon atoms) are obtained by condensing 9 - isopropylidene - 9,10 - dihydroanthracene - 10-carboxylic acid chloride with a b -aminoethanol of the formula FORM:1078250/C2/2 wherein R1 and R2 are as defined above, e.g. b -dimethylamino-, b -diethylamino-, b -methylethylamino-, b -methylbutylamino-, b -methylisopropylamino or b -ethylbutylaminoethanol. The products form non-toxic acid addition salts. 9 - Isopropylidene - 9,10 - dihydroanthracene - 10 - carboxylic acid chloride is obtained from the corresponding acid with a dehydrating agent, e.g. thionyl chloride, phosphorus trichloride or phosphorus pentachloride. Pharmaceutical compositions containing the above novel compounds and having a spasmolytic activity are administered orally, parenterally, or rectally.