(A) Process: A=R4-phenyl or pyridyl; R1 and R2=H, halogen, CF3 or nitro; R3=H or low alkyl; R4=H or halogen; L=a group which can be split off such as a ha

摘要

(A) Process: A=R4-phenyl or pyridyl; R1 and R2=H, halogen, CF3 or nitro; R3=H or low alkyl; R4=H or halogen; L=a group which can be split off such as a halogen atom or a sulphonyloxy group. (B) Compounds of formula (II) where A= a 6-pyridyl group pref. connected with the benzoxadiazocine nucleus at the 2-pos of the pyridyl group; R2=preferably H; R1=preferably halogen such as Cl or Br at the 8-pos. of the benzoxadiazocine nucleus. Compounds (II) are important intermediates in the synthesis of compounds with sedative, muscle-relaxant and anti-convulsive properties. The 1,3-dihydro 6-pyridyl 2H-4, 1,5-benzoxadiazocine 2-ones have also sedative-, muscle relaxant and anti-convulsive properties. The new process is simple and gives good yields. Compounds (III) where A=pyridyl can be easily synthesised from easily obtainable starting materials.