A PROCESS FOR THE PRODUCTION OF STREPTOMYCINE FROM STREPTOMYCES GRISEUS STRAIN 32-13.

摘要

A method known per se of producing streptomycine by cultivation of strain of streptomyces griseus by sub-merged culture rnethod under aerolic conditions. Wherein a strain 32-13 of streptomyces griseus is used which strain is charac- terized by the following properties: on solidified synthetic medium with glucose forms on the 12th day wrinkled colonies 4-5 mm in diameter, devoid of spores; on Gauze"s synthetic medium, forms colonies 3-4 mm in diameter with grey aerial and substrate mycelium, devoid oE spores; on Gaud"s organic medium forms colonies 4-5 mm in diameter with weakly developed aeriat mycelium, devoid of ipores, on organic medium with maize extract farms colonies with bent speculating hyphae with large oval spores; on cellulose, weak growth en the 15th day; liquefies gelatine to.three-fourths of the volume on the 5th day; when fermentation carried out in liquid organic medium in submerged conditions synthesizes streptomycine to the amount of 4500-9000 units per millimeter; resistant to the lytic action oF actinophage.