2-Aminobenzylamine derivs prepn. - by direct amination of 2-aminobenzyl derivs, used as secretolytics and anti-tussives

摘要

Title cpds. of formula (I) (where R1 = H, Cl or Br; R2 = H or 1-3C alkyl; R3 = cyclohexyl opt. substd. by OH and R4 = H; or R3 = isopropylaminocarbonylmethyl, or morpholinocarbonylmethyl and R4 = H or PhCHO and X1 = Cl or Br) are prepd. by condensing a halide, acyloxy or sulphonyloxy deriv. of the corresp. benzyl alcohol, with an amine R2R3NH.